WHAT IS     
MYASTHENIA
GRAVIS?
Myasthenia Gravis (MG) is a very rare and chronic  AUTOIMMUNE  NEUROMUSCULAR  disorder. It is characterized by over active antibody production that results in muscle weakness. This disorder was once thought to only affect adults, but MG is now being discovered in children.

This disorder is considered a ‘snowflake’ disorder because no two patients experience the exact same symptoms. However, the most common symptoms include fluctuating weakness and fatigue of voluntary muscles in the eyes, face, or in the mouth and throat while chewing or swallowing. Breathing muscles can also be affected.

   NEUROMUSCULAR  
Refers to nerves and muscles.

   TERMS:    

   AUTOIMMUNE  
Refers to cases when the immune system
attacks and damages its own cells or tissues.

    WHAT DOES  
MG MEAN?
The term “myasthenia gravis” literally translates to severe muscle weakness. In Greek, myasthenia means ‘muscle weakness,’ and gravis is the Latin word for ‘severe.’

Pediatric MG is strongly influenced by genetic and environmental factors, and it is generally associated with antibodies to the acetylcholine (NEUROTRANSMITTERS) receptors. The exact cause is unknown, but MG symptoms can be medically managed with treatment and education. Chances of remission are higher in young children.

   TERMS:    

   NEUROTRANSMITTERS  
These are chemicals that nerves use to communicate information throughout our brain and body.

WHAT ARE     
PEDIATRIC VARIATIONS OF MG?

  NEONATAL MYASTHENIA GRAVIS   
Occurs in babies born to myasthenic mothers

  CONGENITAL MYASTHENIA SYNDROME (CMS)  
A group of uncommon hereditary neuromuscular disorders which are different from the autoimmune disorder, myasthenia gravis

  OCULAR MYASTHENIA GRAVIS  
Patients with this variation of MG only have weakness in the muscles controlling the eye, but this can progress to more general MG symptoms as a person ages

MGKIDS MISSION

At MGKids we are a community focused on educating, advocating, and supporting children with Myasthenia Gravis (MG) as well as their parents, caregivers, and educators. The patient and family come first with MGKids. We will provide you the necessary tools to seek care, educate, and raise awareness for MG.